Research

Current research projects

Establishment and validation of the exposome as a prognostic predictor of female fertility

Determining the exposome of female fertility patients, and if it is useful predictor of fertility outcomes.
Collaborators: Dr. Brad Clarke, Prof. Luk Rombauts, Dr. Debra Gook

Utilising male fertility as a biomarker of health to understand the biological effects of PFAS

Understanding how PFAS exposure effects male fertility, and whether male fertility is a biomarker of PFAS exposure.
Collaborators: Prof. Brett Nixon, Dr. Geoff De Iuliis, Dr. Shaun Roman (The University of Newcastle)

The impact of environmental toxicants on the fertility of female animals

Determining the effects of environmental toxicants on female fertility across generations in mouse and marsupial models.
Collaborators: Dr. Karla Hutt (Monash University), Dr. Jodi Flaws (University of Illinois), Dr. Oliver Hutt (CSIRO).

Environmental pollutants and embryo development

Determining the effects of endocrine disruptors on embryo developmental competence and metabolism.
Collaborators: Prof Andrew Pask (School of BioSciences), Dr Alex Harvey (School of BioSciences.

Sperm microfluidics

Development of microfluidic devices to improve sperm quality of males undergoing fertility treatment, which should increase fertilisation and pregnancy rates.
Collaborators: Dr Bryon Wright (University of Auckland, New Zealand), A/Prof Richard Fry (University of Melbourne)

Mitochondrial function and ovarian aging

Understanding the impact of maternal age and ovarian stimulation regimens on changes in the mitochondrial characteristics that modulate oocyte and embryo development.
Collaborators: Dr Lynsey Cree, A/Prof. Andrew Shelling (University of Auckland, New Zealand)

Antioxidants and reproduction

Does melatonin, as a powerful antioxidant, protect against the potentially detrimental impact of urban lighting on health and species ‘fitness’.
Collaborators: A/Prof Theresa Jones (School of BioSciences), Metabolomics Australia

IVF children phenotype

Follow-up studies of children born through IVF to determine if differences are evident in their body composition, blood metabolites and hormones when compared to naturally conceived children.
Collaborators: Prof. Wayne Cutfield (University of Auckland, New Zealand), Dr John Peek (Fertility Associates Ltd., New Zealand)

The health of cloned animals

Investigations to determine the health of cloned cattle from early pregnancy through to old age.
Collaborators: Dr Rita Lee, Dr Dave Wells (AgResearch Ltd., New Zealand)

Uterine infection and reproductive potential

Studies to establish the long-term effects of uterine infection after parturition on subsequent ovarian function.
Collaborators: Dr Penny Back (Massey University, New Zealand), Prof Ken McNatty (Victoria University, New Zealand)


Patents

Green MP, Wright BE (2013) Method and apparatus for the isolation of motile sperm. Filed in the New Zealand (PCT NZ2013/000026, Feb 2013) and Australia (2013226583), USA (14/382046) and EU (W02013129947) Sept 2014. This patent is held by BWMG Ltd and is under an exclusivity agreement with an option to license to Genea Biomedx, Pty.

Green MP, Berg D, Lee RSF, Berg MC (2010) Livestock parturition to conception interval reduction strategy. NZ Patent office (PCT/NZ2011/000636), filed June 2011. Held by AgResearch Ltd and is under an exclusivity agreement to MSD (Merck Sharpe Dohme) Animal Health, NZ.